Endocrine Abstracts

The proximate cause of functional hypothalamic amenorrhea (FHA) is reversible suppression of GnRH drive that results in chronic anovulation and low estradiol levels that preclude endometrial growth and shedding. Clinical management of FHA requires not only understanding the neuromodulation of GnRH drive, but also how cognitive and behavioral concomitants suppress GnRH drive. FHA results in a constellation of neuroendocrine concomitants that include activation of the hypothalam...